Wood TWP and Nakamura T
Problems in Fish-to-Tetrapod Transition: Genetic Expeditions into Old Specimens
Front. Cell Dev. Biol. 2018

Letelier J, Calle-Mustienes E, Pieretti J, Naranjo S, Maeso I, Nakamura T, Pascual-Anaya J, Shubin NH, Schneider I, Martinez-Morales JR & Gómez-Skarmeta JL.
A conserved Shh cis-regulatory module highlights a common developmental origin of unpaired and paired fins
Nature Genetics. 2018


Nakamura T*, Gerhke AR*, Lemberg J, Szymaszek J, Shubin NH (*contributed equally to this work)
Digits and fin rays share common developmental histories.
Nature. 2016 Aug 17;537(7619):225-228
"From Fins into Hands; Scientists Discover a Deep Evolutionary Link "   Reported on The New York Times 2016 Aug 17
NEWS&VIEWS, Evolutionary biology: Fin to limb within our grasp, Nature 2016 Sep 537, 176-177

Inaba Y, Shinohara K, Bottled Y, Nabeshima R, Takaoka K, Ajima R, Lamri L, Takeda H, Saga Y, Nakamura T, Hamada H.
Transport of the outer dynein arm complex to cilia requires a cytoplasmic protein Lrcc6.
Genes Cells. 2016 Jul;21(7):728-39.

Braasch I, Gehrke AR, Smith JJ, Kawasaki K, Manousaki T, Pasquier J, Amores A, Desvignes T, Batzel P, Catchen J, Berlin AM, Campbell MS, Barrell D, Martin KJ, Mulley JF, Ravi V, Lee AP, Nakamura T et al.
The spotted gar genome illuminates vertebrate evolution and facilitated human-teleost comparisons.
Nature Genetics. 2016 Apr;48(4):427-37                                                                                                                   


Nakamura T, Klomp J, Pieretti J., Schneider I.,Gerhke AR., Shubin NH.
Molecular mechanisms underlying the exceptional adaptations of batoid fins.
Proc Natl Acad Sci U S A. 2015 Dec 29; 112(52):15940-5.  
Pieretti J, Gehrke AR, Schneider I, Adachi N, Nakamura T, Shubin NH.
Organogenesis in deep time: A problem in genomics, development, and paleontology.
Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):4871-6
Gehrke AR, Schneider I, de la Calle-Mustienes E, Tena JJ, Gomez-Marin C, Chandran M, Nakamura T, Braasch I, Postlethwait JH, Gómez-Skarmeta JL, Shubin NH.
Deep conservation of wrist and digit enhancers in fish.
Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):803-8


Dong F, Shinohara K, Botilde Y, Nabeshima R, Asai Y, Fukumoto A, Hasegawa T, Matsuo M, Takeda H, Shiratori H, Nakamura T and Hamada H.
Pih1d3 is required for cytoplasmic pre-assembly of axonemal dynein in mouse sperm.
Journal of Cell Biology, 2014 Jan 20;204(2):203-13


Inácio JM, Marques S, Nakamura T, Shinohara K, Meno C, Hamada H, Belo JA.
The dynamic right-toleft translocation of Cerl2 is involved in the regulation and termination of Nodal activity in the mouse node.
PLoS One. 2013. 8(3):e60406


Nakamura T, Saito D, Kawasumi A, Shinohara K, Asai Y, Takaoka K, Dong F, Takamatsu A, Belo JA, Mochizuki A, Hamada H.
Fluid flow and interlinked feedback loops establish left-right asymmetric decay of Cerl2 mRNA.
Nature Communications. 2012;3:1322.
Lei Z, Maeda T, Tamura A, Nakamura T, Yamazaki Y, Shiratori H, Yashiro K, Tsukita S, Hamada H.
EpCAM contributes to formation of functional tight junction in the intestinal epithelium by recruiting claudin proteins.
Developmental Biology. 2012 Nov 15;371(2):136-45.

Nakamura T, Hamada H.
Left-right patterning: conserved and divergent mechanisms.
Development. 2012 Sep;139(18):3257-62.

Kawasumi.A, Nakamura T, Iwai N, Yashiro K, Saijoh Y, Belo J, Shiratori H, Hamada H.
Left-right asymmetry of Nodal activity in the node is translated into left-right asymmetry in the lateral plate of mouse embryos.
Developmental Biology2011, 2011 May 15;353(2):321-30.  

Tanaka C, Sakuma R, Nakamura T, Hamada H, Saijoh Y.
Long-range action of Nodal requires interaction with GDF1.
Genes and Development. 2007 Dec 15;21(24):3272-82.


Nakamura T, Mine N, Nakaguchi E, Mochizuki A, Yamamoto M, Yashiro K, Meno C, Hamada H.
Generation of robust left-right asymmetry in the mouse embryo requires a self- enhancement and lateral-inhibition system.
Developmental Cell, 11, 495-504, 2006


Saijoh Y, Oki S, Tanaka C, Nakamura T, Adachi H, Yan YT, Shen MM, Hamada H.
Two nodal-responsive enhancers control left-right asymmetric expression of Nodal. 
Developmental Dynamics, 232(4);1031-1036; 2005


Takagi M, Nakamura T, Matsuda C, Hattori T, Wakitani S, Yoshida T.
In vitro proliferation of human bone marrow mesenchymal stem cells employing donor serum and basic fibroblast growth factor.